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Combination Prevention

Expanded high-impact prevention is needed to bring the epidemic to a conclusive end.

Combination or high-impact prevention is a set of strategically-selected interventions that matches the needs of a given country or community—and is delivered at the scale needed to make an impact. It means doing less of something and far more of others. It means making tough decisions and measuring impact. Above all, it means moving with clarity and speed.

There are emerging global definitions of what combination prevention is, and evolving models of what it can achieve. AVAC works with advocates to define what combination prevention means in a given context, track country and donor alignment with a combination prevention strategy and ensure that there is an implementation science agenda to fill in gaps in knowledge. 

What We're Reading

HIV Prevention for the Next Decade: Appropriate, person-centred, prioritised, effective, combination prevention

A range of exciting new HIV prevention technologies have become available or are in the pipeline but will only have an impact if they are accessible and affordable and delivered within systems that take full account of the social and political context in which most infections occur.

November 4, 2022
Combination Prevention
PLOS Medicine

UN Shift on HIV Prevention Raises Hope We Can End AIDS by 2030

The latest UN Declaration on AIDS does not speak more forcefully on the need to protect the human rights of key populations at risk for HIV, but there are significant shifts, including an unprecedented commitment to HIV combination prevention.

July 16, 2021
Combination Prevention
Daily Maverick
Featured Resources

Combination Prevention: Integrating strategies to end the epidemic

One-pager describing what "combination prevention" means.

November 2022
AVAC
Combination Prevention
Fact Sheet

AVAC Report 2019: Now What?

At the threshold of 2020, it’s clear that global goals for HIV prevention will miss the mark by a long shot. Though important progress has been made, the crisis UNAIDS called out in 2016 persists today with new infections around 1.7 million annually, a far cry from the 2020 target of fewer than 500,000. So, we asked ourselves, Now What?, and answered with cross-cutting analysis and an advocacy agenda to match.

November 2019
AVAC
HIV Vaccine, Combination Prevention, Male and Female Condoms, Cure, Hormonal Contraceptives and HIV, Microbicides, Multipurpose Prevention Technologies, PrEP, Treatment, Voluntary Medical Male Circumcision
AVAC Report
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